Journal of Natural Science, Biology and Medicine

ORIGINAL ARTICLE
Year
: 2011  |  Volume : 2  |  Issue : 1  |  Page : 113--118

Fine needle aspiration cytology as the primary diagnostic tool in thyroid enlargement


Arup Sengupta1, Ranabir Pal2, Sumit Kar2, Forhad Akhtar Zaman2, Subhabrata Sengupta3, Shrayan Pal2 
1 Department of Otorhinolaryngology, M.G.M. Medical College, Kisanganj, Bihar, India
2 Department of Community Medicine, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
3 Department of Otorhinolaryngology, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India

Correspondence Address:
Ranabir Pal
Department of Community Medicine, Sikkim Manipal Institute of Medical Sciences (SMIMS), 5th Mile, Tadong, Gangtok, Sikkim - 737 102
India

Background: In the preoperative decision-making of the thyroid swellings, fine needle aspiration cytology (FNAC) is becoming an ever more vital tool. Objectives: To compare the advantage of preoperative FNAC of thyroid swellings with postoperative histopathology to reach a consensus protocol as a simple procedure for diagnosis and optimal management of thyroid swellings. Materials and Methods: A prospective study of preoperative FNAC was carried out on 178 incidental thyroid swellings attending a tertiary care centre in Kishanganj, Bihar. Evidence-based surgical interventions were done, irrespective of FNAC findings and diagnosis was confirmed by histopathological examination (HPE) postoperatively in all the cases. Results: In the FNAC, preponderance of the cases (75.84%) was colloid goitre followed by granulomatous thyroiditis; follicular carcinoma was noted in 7.30 percent and anaplastic carcinoma in 3.37 percent of cases. Histopathological examination showed colloid goitre predominantly (76.97%), followed by follicular carcinoma (8.99%). The overall prevalence of malignancy was 11.24 percent diagnosed by HPE and 9.55 percent by FNAC. In our FNAC series sensitivity of was 90 percent while specificity was 100 percent; accuracy was 98.88 percent. Predictive value of a positive test and negative tests was 100 percent and 98.75 percent respectively. Conclusion: The study highlights that FNAC should be treated as a first-line diagnostic test for thyroid swellings to guide the management though this is not a substitute for HPE as a need to improve primary healthcare in India.


How to cite this article:
Sengupta A, Pal R, Kar S, Zaman FA, Sengupta S, Pal S. Fine needle aspiration cytology as the primary diagnostic tool in thyroid enlargement.J Nat Sc Biol Med 2011;2:113-118


How to cite this URL:
Sengupta A, Pal R, Kar S, Zaman FA, Sengupta S, Pal S. Fine needle aspiration cytology as the primary diagnostic tool in thyroid enlargement. J Nat Sc Biol Med [serial online] 2011 [cited 2021 Jan 23 ];2:113-118
Available from: http://www.jnsbm.org/article.asp?issn=0976-9668;year=2011;volume=2;issue=1;spage=113;epage=118;aulast=Sengupta;type=0