Year : 2018  |  Volume : 9  |  Issue : 2  |  Page : 111-114

Use of intralipid in the management of recurrent implantation failure: An overview

1 Department of Obstetrics and Gynecology, National Guard Health Affairs, Kind Abdulaziz Medical City, Riyadh, Saudi Arabia
2 Department of Research, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia

Correspondence Address:
Shoeb Qureshi
Department of Research, College of Applied Medical Sciences, Kind Saud bin Abdul-Aziz University for Health Sciences, Riyadh
Saudi Arabia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jnsbm.JNSBM_246_17

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Recurrent embryo implantation failure is a disorder with potentially dreadful physiological and psychological manifestations for those who are affected. Embryo implantation and formation of a functional placenta are processes that require a plethora of regulatory mechanisms involving both maternal and embryonic cells. In the ensuing overview, an attempt is made to understand (1) the pathophysiology of recurrent unexplained implantation failure (2) the available evidence for the two popular treatment modalities, i.e., intravenous immune globulin and intralipid, (3) the limitation of current available data, (4) the pathophysiology and immunomodulatory treatment options for recurrent implantation failure to address the pathological, psychological, and financial distress, and associated impact on couple's quality of life.

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