Year : 2017  |  Volume : 8  |  Issue : 2  |  Page : 176-180

Isolation and antibiotic susceptibility pattern of Escherichia coli from urinary tract infections in a tertiary care hospital of North Eastern Karnataka

1 Department of Microbiology, Shri B.M Patil Medical College and research centre, BLDE University, Vijayapura, India
2 Department of Microbiology, Raichur Institute of Medical Sciences, Raichur, Karnataka, India
3 Department of Physiology, Little Flower Institute of Medical Sciences and Research, Angamaly, Kerala, India

Correspondence Address:
Sudheendra Ramesh Kulkarni
Department of Microbiology, BLDE's Shri B M Patil Medical College, Bijapur, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0976-9668.210012

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Introduction: Clinical management of the urinary tract infections (UTI) is influenced by the antimicrobial vulnerability patterns. Objective: The study aimed to analyse the resistance pattern of the Escherichia coli (E. coli) causing UTI in patients over a period of 4 years from 2012 to 2015. Materials and Methods: 1000 samples from patients suspected of having urinary tract infections were collected and processed for culture and antimicrobial drug susceptibility as per the routine microbiological techniques. Results: Of the total 1000 samples, 395 cases were culture-positive for E. coli. These isolates were tested for antibiotic susceptibility by disk diffusion method. Of the total 395 E. coli isolates, 170 (43%) were multi drug resistant (MDR). The isolates showed high level of resistance to Ampicillin (82.53%), Cefuroxime (72.41%), Amoxycillin-clavulinic acid (71.90%), Ceftriaxone (66.58%), Ciprofloxacin (65.82%) and Cefepime (57.47%). The isolates were sensitive to Imipenem (96.71%), Nitrfurantion (92.41%), Amikacin (90.89%), Chloramphenicol (85.82%), Piperacillin-tazobactum (80.76%), Gentamicin (59.24%), Azetreonam (54.43%) and Norfloxacin (53.67%). Conclusion: We conclude that a significant number of the urinary tract infections in our study subjects were caused by multiple drug resistant E. coli. The sensitivity pattern showed a continued decline from 2012 to 2015, with Imipenem being currently the most effective antibiotic.

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