ORIGINAL ARTICLE
Year : 2015  |  Volume : 6  |  Issue : 2  |  Page : 340-342

Effects of fluconazole, chlorhexidine gluconate, and silver-zinc zeolite on flexural strength of heat-cured polymethyl methacrylate resin


Department of Maxillofacial Prosthodontics and Implantology, Peoples Dental Academy, Bhopal, Madhya Pradesh, India

Correspondence Address:
Dr. Sunil Kumar Mishra
Department of Maxillofacial Prosthodontics and Implantology, Peoples Dental Academy, Bhopal, Madhya Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9668.159999

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Aim: We evaluated the effect of incorporating Fluconazole, Chlorhexidine Gluconate, and Silver-Zinc Zeolite as bioactive materials (10% of mass) on the flexural strength of commercially available heat-cured polymethyl methacrylate (PMMA; Travelon). Materials and Methods: The following four groups were compared; Group 1: Control group with pure PMMA, Group 2: Antibacterial drug group with chlorhexidine gluconate in powder form + PMMA, Group 3: Antifungal drug group with fluconazole in powder form + PMMA, Group 4: Antimicrobial agent group with silver zinc zeolite in powder form + PMMA. After processing, the specimens were subjected for flexural strength testing using three-point bending test in a universal testing machine. Results: A significant (P < 0.0001) decrease in flexural strength following incorporation of Fluconazole, Chlorhexidine Gluconate, and Silver-Zinc Zeolite to heat polymerized acrylic resin was observed when compared with the control group. The decrease in mean flexural strength was minimal in the fluconazole group. Conclusion: Although the addition of a bioactive material to PMMA acrylic is desirable, it is not practical as it reduces flexural strength of the acrylic base.


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