REVIEW ARTICLE
Year : 2014  |  Volume : 5  |  Issue : 1  |  Page : 3-7

Chemoprevention of oral cancer: Green tea experience


1 Department of Preventive Oncology, Cancer Institute (WIA), Gandhi Nagar, Tamil Nadu, India
2 Department of Surgical Oncology, Cancer Institute (WIA), Sadar Patel Road, Adyar, Chennai, Tamil Nadu, India

Correspondence Address:
Vijayalakshmi Ramshankar
Department of Preventive Oncology, Cancer Institute (WIA), No 1, East Canal Bank Road, Gandhi Nagar, Adyar, Chennai - 600 020, Tamil Nadu
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9668.127272

Rights and Permissions

Oral cancer has a well characterized progression from premalignant oral epithelial changes to invasive cancer, making oral squamous cell carcinoma an optimal disease for chemoprevention interventions prior to malignant transformation. The primary goal of chemoprevention here is to reverse, suppress, or inhibit the progression of premalignant lesions to cancer. Due to the extended duration of oral pathogenesis, its chemoprevention using natural products has been found promising due to their decreased dose and limited toxicity profiles. This review discusses with an emphasis on the clinical trials using green tea extract (GTE) in chemoprevention of oral premalignant lesions along with use of GTE as a chemopreventive agent in various other cancers as well. It is worthwhile to include green tea extract in an oral screening program for evaluating the premalignant lesions comparing the results between the treated and untreated group. Given the wide acceptance of green tea, its benefits may help in effective chemoprevention oral cancer.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed4441    
    Printed80    
    Emailed1    
    PDF Downloaded970    
    Comments [Add]    
    Cited by others 12    

Recommend this journal