Year : 2014  |  Volume : 5  |  Issue : 1  |  Page : 186-190

Metachronous multifocal myxoid liposarcoma involving the gastrointestinal tract. Management and literature review

1 Department of Surgery, Army General Hospital, Athens, Greece Europe
2 Department of Medical Oncology, Army General Hospital, Athens, Greece, Europe

Correspondence Address:
Nikolaos S Salemis
19 Taxiarhon Str, 19014 Kapandriti, Athens, Greece, Europe

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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0976-9668.127325

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Multifocal soft tissue sarcoma is a rare clinical entity occurring in 1% of patients with extremity soft tissue sarcoma and in 4.5% of patients with liposarcoma. Multifocal disease may arise either synchronously or metachronously and has been associated with poor prognosis. Herein, we have described a rare case of metachronous multifocal myxoid liposarcoma involving the gastrointestinal tract that developed 14 months after the resection of a myxoid buttock liposarcoma. Diagnostic evaluation and management of the patient are discussed along with a review of the relevant literature. We conclude that multifocal myxoid liposarcoma is a rare clinical entity that usually represents metastatic disease with poor prognosis. A thorough imaging and careful physical examination are essential in the preoperative evaluation and postoperative follow-up of patients with myxoid extremity liposarcomas, as these tumors are known to have a tendency to spread toward extrapulmonary sites, frequently without pulmonary metastases.

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