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  Indian J Med Microbiol
 

Figure 4: Schematic showing the signaling events between thermo-TRP channels and PKC. Activation and translocation of cytosolic cPKC βI, II, and nPKCε, δ isoforms to plasma membrane may mediate phosphorylation, and hence modulation of plasma membrane-associated thermo-TRP channels. Diacyglycerol (DAG), Phospholipase C (PLC), Inositol 1,4,5-triphosphate (IP3), intracellular calcium (Ca2+), Phosphatidylcholine (PC), Phospholipase D (PLD), Arachidonic acid (AA), Phospholipase A2 (PLA2), cis-unsaturated fatty acid (FFA), and lysophosphatidylcholine (lysoPC), Inositol phospholipids (IP).

Figure 4: Schematic showing the signaling events between thermo-TRP channels and PKC. Activation and translocation of cytosolic cPKC βI, II, and nPKCε, δ isoforms to plasma membrane may mediate phosphorylation, and hence modulation of plasma membrane-associated thermo-TRP channels. Diacyglycerol (DAG), Phospholipase C (PLC), Inositol 1,4,5-triphosphate (IP3), intracellular calcium (Ca2+), Phosphatidylcholine (PC), Phospholipase D (PLD), Arachidonic acid (AA), Phospholipase A2 (PLA2), cis-unsaturated fatty acid (FFA), and lysophosphatidylcholine (lysoPC), Inositol phospholipids (IP).