Journal of Natural Science, Biology and Medicine

RESEARCH ARTICLE
Year
: 2015  |  Volume : 6  |  Issue : 1  |  Page : 131--138

Diagnostic role of magnetic resonance cholangiopancreatography in evaluation of obstructive biliopathies and correlating it with final diagnosis and clinical profile of patients


Umesh Chandra Parashari1, Sachin Khanduri1, Samarjit Bhadury1, Deepika Upadhyay2, Kaushal Kishore3 
1 Department of Radio Diagnosis, Era's Lucknow Medical College, Lucknow, Uttar Pradesh, India
2 Department of Radio Diagnosis, Sardar Patel Institute of Medical and Dental Sciences, Lucknow, Uttar Pradesh, India
3 Department of Radio Diagnosis, King George's Medical University, Lucknow, Uttar Pradesh, India

Correspondence Address:
Dr. Umesh Chandra Parashari
Department of Radio Diagnosis, Era«SQ»s Lucknow Medical College, Sarfarazganj, Hardoi Road, Lucknow - 226 003, Uttar Pradesh
India

Aims and Objective : We assessed the utility of magnetic resonance cholangiopancreatography (MRCP) as a noninvasive diagnostic tool in patients with obstructive biliopathies. Materials and Methods: A prospective study was conducted on 54 patients with clinically suspected biliary obstruction. MRCP in these patients was compared and correlated with final diagnosis and their clinical profile. Statistical Analysis: Sample profile was described in terms of sensitivity, specificity, positive and negative predictive values, and diagnostic accuracy. Pearson«SQ»s Chi-square statistics was used to assess the strength of association between diagnostic accuracy of MRCP and final diagnosis. Results: Out of the 54 patients, 50 had biliary obstruction. The cause of biliary obstruction was finally identified on the basis of direct cholangiography/surgery/histopathology. In 52 of the 54 patients, MRCP agreed with final diagnosis in identifying the level of block. MRCP agreed with final diagnosis in identifying the cause of obstruction in 48 of the 54 patients (89%). Sensitivity of MRCP in identifying the level of obstruction in comparison with final diagnosis was 100%, while diagnostic accuracy of MRCP in identifying the level of obstruction in comparison with final diagnosis was 96.29%. The correlation between MRCP and final diagnosis in diagnosing cause of obstruction was 0.95 (Pearson«SQ»s correlation coefficient, P = 0.017). Conclusion: MRCP is a safe ionizing radiation and iodinated contrast free modality which has the ability to display the biliary tree by combining the advantages of projectional and cross-sectional imaging.


How to cite this article:
Parashari UC, Khanduri S, Bhadury S, Upadhyay D, Kishore K. Diagnostic role of magnetic resonance cholangiopancreatography in evaluation of obstructive biliopathies and correlating it with final diagnosis and clinical profile of patients.J Nat Sc Biol Med 2015;6:131-138


How to cite this URL:
Parashari UC, Khanduri S, Bhadury S, Upadhyay D, Kishore K. Diagnostic role of magnetic resonance cholangiopancreatography in evaluation of obstructive biliopathies and correlating it with final diagnosis and clinical profile of patients. J Nat Sc Biol Med [serial online] 2015 [cited 2020 Feb 18 ];6:131-138
Available from: http://www.jnsbm.org/article.asp?issn=0976-9668;year=2015;volume=6;issue=1;spage=131;epage=138;aulast=Parashari;type=0