Journal of Natural Science, Biology and Medicine

REVIEW ARTICLE
Year
: 2011  |  Volume : 2  |  Issue : 1  |  Page : 50--52

Periodontitis: A risk for delivery of premature labor and low birth weight infants


Rajiv Saini1, Santosh Saini2, Sugandha R Saini3 
1 Department of Periodontology, Rural Dental College-Loni, Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra, India
2 Department of Microbiology, Rural Dental College-Loni, Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra, India
3 Department of Prosthodontics, Rural Dental College-Loni, Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra, India

Correspondence Address:
Rajiv Saini
Department of Periodontology & Oral Implantology, Rural Dental College- Loni Rahata, Ahmednagar, Maharashtra- 413736
India

Periodontitis is a destructive inflammatory disease of the supporting tissues of the teeth and is caused by specific microorganisms or a group of specific microorganisms. Association of periodontal infection with organ systems like cardiovascular system, endocrine system, reproductive system, and respiratory system makes periodontal infection a complex multiphase disease. Inflamed periodontal tissues produce significant amounts of pro-inflammatory cytokines, mainly interleukin 1 beta (IL-1β), IL-6, prostaglandin E2 (PGE2), and tumor necrosis factor alpha (TNF-α), which may have systemic effects on the host. Low birth weight, defined as birth weight less than 2500 g, continues to be a significant public health issue in both developed and developing countries. Research suggests that the bacteria that cause inflammation in the gums can actually get into the bloodstream and target the fetus, potentially leading to premature labor and low birth weight (PLBW) babies. One reasonable mechanism for this is the deleterious effect of endotoxin released from gram-negative bacteria responsible for periodontal disease. Hence, periodontal disease appears to be an independent risk factor for PLBW and there is a need to expand preventive measures for pregnant women in coordination with the gynecological and dental professions.


How to cite this article:
Saini R, Saini S, Saini SR. Periodontitis: A risk for delivery of premature labor and low birth weight infants.J Nat Sc Biol Med 2011;2:50-52


How to cite this URL:
Saini R, Saini S, Saini SR. Periodontitis: A risk for delivery of premature labor and low birth weight infants. J Nat Sc Biol Med [serial online] 2011 [cited 2020 Sep 18 ];2:50-52
Available from: http://www.jnsbm.org/article.asp?issn=0976-9668;year=2011;volume=2;issue=1;spage=50;epage=52;aulast=Saini;type=0