REVIEW ARTICLE
Year : 2018  |  Volume : 9  |  Issue : 1  |  Page : 2-5

Tea polyphenols and prevention of epigenetic aberrations in cancer


1 Department of Medical Biotechnology, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok, Sikkim, India
2 Department of Horticulture, Sikkim University, Gangtok, Sikkim, India

Correspondence Address:
Arundhati Bag
Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok - 737 102, Sikkim
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jnsbm.JNSBM_46_17

Rights and Permissions

Tea polyphenols are secondary metabolites of tea plants and are well known for beneficial health effects. They can protect from a variety of illnesses including cancers. Tea polyphenols can prevent cancer by modulating epigenetic aberrations taking place in DNA methylation, histone modifications, and micro-RNAs. By altering these epimutations, they regulate chromatin dynamics and expression of genes those induce or suppress cancer formation. However, majority of the studies in existing literature are carried out for green tea polyphenols rather than black tea polyphenols despite the fact that black tea is the most commonly consumed form of tea (78%) followed by green tea (20%) and other forms of tea. Research findings indicate that tea polyphenols may be potential source from which drugs with less side effects and affordable price can be developed.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed356    
    Printed10    
    Emailed0    
    PDF Downloaded132    
    Comments [Add]    

Recommend this journal