ORIGINAL ARTICLE
Year : 2016  |  Volume : 7  |  Issue : 2  |  Page : 124-126

PreFRP: Prediction and visualization of fluctuation residues in proteins


1 Centre of Excellence in Bioinformatics, School of Biotechnology, Madurai Kamaraj University, Madurai, India
2 Department of Bioinformatics, School of Biosciences, The Marudupandiyar Institutions (Affiliated to Bharathidasan University), Thanjavur, Tamil Nadu, India

Correspondence Address:
Renganathan Senthil
Department of Bioinformatics, School of Biosciences, The Marudupandiyar Institutions (Affiliated to Bharathidasan University), Thanjavur - 613 403, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9668.184696

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Aim: The PreFRP web server extracts sequence and basic information of a protein structure and groups amino acid residues in a protein into three important types such as high, moderate, and weak fluctuating residues. Materials and Methods: The server takes a protein data bank file or an amino acid sequence as input and prints the probability of amino acid residues to fluctuate. The server also provides a link to Jmol, a molecular visualization program to visualize the high, moderate, and weak fluctuating residues in three different colors. Results: Prediction and visualization of fluctuating amino acid residues in proteins may help to understand the complex three-dimensional structure of proteins and may further help in docking and mutation experiments. Availability: The web server is freely accessible through the web page of the author's institution http://www.mpi.edu.in/prefrp/link.html.


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