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Year : 2011  |  Volume : 2  |  Issue : 3  |  Page : 9  

Predicting bio-molecular interactions in proteins and nucleic acids


National Institute of Biomedical Innovation, 7-6-8 Asagi-Saito, Ibaraki-City, Osaka, 567-0085, Japan

Date of Web Publication26-May-2012

Correspondence Address:
Shandar Ahmad
National Institute of Biomedical Innovation, 7-6-8 Asagi-Saito, Ibaraki-City, Osaka, 567-0085
Japan
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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Ahmad S. Predicting bio-molecular interactions in proteins and nucleic acids. J Nat Sc Biol Med 2011;2, Suppl S1:9

How to cite this URL:
Ahmad S. Predicting bio-molecular interactions in proteins and nucleic acids. J Nat Sc Biol Med [serial online] 2011 [cited 2020 Mar 31];2, Suppl S1:9. Available from: http://www.jnsbm.org/text.asp?2011/2/3/9/95724

All biological functions can ultimately be described in terms of interactions between proteins, nucleic acids and other smaller molecules. Molecular interactions provide for the enormous complexity of events in living systems despite a relatively smaller number of constituent entities. Identifying molecules throughout an organism's cellular makeup is much easier than detecting all possible interactions amongst them or predicting the conditions in which they take place. Bioinformatics approaches to predict interactions from the knowledge of molecular features are required to fill this gap. We have extensively studied statistical nature of bio-molecular interactions and developed computational technologies to predict them from sequence and structure. Rigorous application of our methods has guided design of biological experiments and has been successful in discovering novel interactions. In this talk, I will review some of these recent success stories.




 

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