ORIGINAL ARTICLE
Year : 2011  |  Volume : 2  |  Issue : 2  |  Page : 211-215

Spectrum of Guillain-Barré syndrome in tertiary care hospital at Kolkata


1 Department of Anesthesiology, Institute of Postgraduate Medical Education and Research, Kolkata, India
2 Department of Community Medicine, Sikkim Manipal Institute of Medical Sciences and Central Referral Hospital (CRH), Gangtok, Sikkim, India
3 Department of Emergency Medicine, Caboolture Hospital, Caboolture, Queensland, Australia
4 Department of Anesthesiology, North Bengal Medical College and Hospital, Darjeeling, India
5 Department of Anesthesiology, RG Kar Medical College, Kolkata, India

Correspondence Address:
Ranabir Pal
Department of Community Medicine, Sikkim Manipal Institute of Medical Sciences and Central Referral Hospital 5th Mile, Tadong, Gangtok, Sikkim - 737 102
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9668.92320

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Objective: In childhood Guillain-Barré syndrome (GBS), the clinical profiles using intravenous immunoglobulin (IVIg) in addition to supportive care were studied. Materials and Methods: This was a retrospective analysis of 139 children with severe GBS admitted to our respiratory care unit managed with the IVIg as an adjunct intervention to conventional supportive and respiratory care. Results: In our case series of 139 cases, motor weakness was the most common presenting feature. Antecedent illness was found in 66.7% of cases in the preceding two weeks, which included nonspecific illness, acute respiratory infection, diarrhea, and chickenpox. At onset, sensory symptoms (pain and paresthesia) were noted in 59% of the cases and limb weakness in 77%. On admission, a majority (61.54%) were in Hughes neurological disability grading stage V; all had limb weakness at the peak deficit, autonomic disturbance was seen in 35.8%, and bulbar palsy in 52%. Duration of illness was less than three weeks in 67% of cases. The mean duration of ventilation was 21.5 days (range, 5-60 days). Conclusions: Male preponderance and motor weakness was the most common presenting illness and a majority achieved full recovery in our series. Although IVIg may be useful in the treatment of GBS, the key issue is excellent intensive care unit management.


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