NATURAL SCIENCE
Year : 2010  |  Volume : 1  |  Issue : 1  |  Page : 2-5

Orodispersible tablets: A new trend in drug delivery


1 Department of Pharmaceutics, Bengal School of Technology, Sugandha, Delhi Road, Hooghly, India
2 Gupta College of Technological Sciences, Ashram More, G.T. Road, Asansol, West Bengal, India

Correspondence Address:
Paramita Dey
Bengal School of Technology, Sugandha, Delhi Road, Hooghly - 712 102, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9668.71663

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The most common and preferred route of drug administration is through the oral route. Orodispersible tablets are gaining importance among novel oral drug-delivery system as they have improved patient compliance and have some additional advantages compared to other oral formulation. They are also solid unit dosage forms, which disintegrate in the mouth within a minute in the presence of saliva due to super disintegrants in the formulation. Thus this type of drug delivery helps a proper peroral administration in pediatric and geriatric population where swallowing is a matter of trouble. Various scientists have prepared orodispersible tablets by following various methods. However, the most common method of preparation is the compression method. Other special methods are molding, melt granulation, phase-transition process, sublimation, freeze-drying, spray-drying, and effervescent method. Since these tablets dissolve directly in the mouth, so, their taste is also an important factor. Various approaches have been taken in order to mask the bitter taste of the drug. A number of scientists have explored several drugs in this field. Like all other solid dosage forms, they are also evaluated in the field of hardness, friability, wetting time, moisture uptake, disintegration test, and dissolution test.


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