BIOLOGY
Year : 2010  |  Volume : 1  |  Issue : 1  |  Page : 12-15

Antibacterial activity of garlic extract on streptomycin-resistant Staphylococcus aureus and Escherichia coli solely and in synergism with streptomycin


1 Aditya Institute of Pharmaceutical Sciences and Research, A.D.B. Road, Aditya Nagar, Surampalem, East Godavari District, Andhra Pradesh, India
2 Department of Pharmacology, Sri Siddaganga College of Pharmacy, B. H. Road, Tumkur, Karnataka, India

Correspondence Address:
M N Palaksha
Aditya Institute of Pharmaceutical Sciences and Research, A. D. B. Road, Aditya Nagar, Surampalem, East Godavari District, Andhra Pradesh - 533 437
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9668.71666

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This study focuses the significant antibacterial activity of Garlic (Allium sativum Linn.) extract on streptomycin-resistant strains solely and in synergism with streptomycin. Gram-positive Staphylococcus aureus ATCC BAA 1026 and gram-negative Escherichia coli ATCC 10536 were made resistant to standard antibiotic streptomycin used as a control in the experiment. Zones of inhibition of different treatment groups were measured by agar-well-diffusion assay and compared with control. Statistical comparison of sole extract and streptomycin synergism with streptomycin control had proved it significant.


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